SCHEMBL30926577

SCHEMBL30926577

O=C(Nc1ccccc1)c1ccccc1NS(=O)(=O)c1cccc(C(F)(F)F)c1

nearest known ligand 0.76

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.76
▸ KMT2A Q03164 2/20 0.76
▸ GAA P10253 1/20 0.76
▸ RXFP1 Q9HBX9 12/20 0.63
▸ SLC20A2 Q08357 1/20 0.62
▸ SLC20A1 Q8WUM9 1/20 0.62
▸ SLC10A2 Q12908 1/20 0.60
▸ SLC10A1 Q14973 1/20 0.60
▸ SLC10A6 Q3KNW5 1/20 0.60
▸ ACLY P53396 1/20 0.59
▸ GPR27 Q9NS67 2/20 0.58
▸ AVPR2 P30518 1/20 0.58
▸ LMNA P02545 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7128448 1.00 MEN1 (0.76) MEN1KMT2AGAARXFP1SLC20A2
SCHEMBL30926819 0.92 MEN1 (0.68) MEN1KMT2AGAARXFP1SLC20A2
SCHEMBL27181165 0.92 MEN1 (0.68) MEN1KMT2AGAARXFP1SLC20A2
SCHEMBL23200355 0.91 MEN1 (0.67) MEN1KMT2AGAARXFP1SLC20A2
SCHEMBL7120286 0.91 SLC20A2 (0.74) MEN1KMT2AGAARXFP1SLC20A2
SCHEMBL30926890 0.91 MEN1 (0.67) MEN1KMT2AGAARXFP1SLC20A2
SCHEMBL28454669 0.87 MEN1 (0.64) MEN1KMT2AGAARXFP1SLC20A2
SCHEMBL14113176 0.86 MEN1 (0.61) MEN1KMT2AGAARXFP1SLC10A2
SCHEMBL30788318 0.85 ALDH1A1 (0.74) MEN1KMT2AGAARXFP1SLC10A2
SCHEMBL30788312 0.85 ALDH1A1 (0.66) MEN1KMT2AGAASLC20A2SLC20A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240099300-A1 SULFONAMIDE APYRASE INHIBITORS TEXAS CROP SCIENCE, INC. 2024-03-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240099300-A1 SULFONAMIDE APYRASE INHIBITORS APEH, ARSA, DNPEP MEN1 4795/4885KMT2A 2544/4885GAA 159/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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