Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.63 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.63 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.61 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.61 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200355 | 1.00 | MEN1 (0.67) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL7128448 | 0.91 | MEN1 (0.76) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL30926577 | 0.91 | MEN1 (0.76) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL27181165 | 0.90 | MEN1 (0.68) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL30926819 | 0.90 | MEN1 (0.68) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL7120286 | 0.89 | SLC20A2 (0.74) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL23200349 | 0.88 | KDM4E (0.63) | MEN1KMT2ASLC10A2SLC10A1SLC10A6 | |
| SCHEMBL28454669 | 0.85 | MEN1 (0.64) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL30927042 | 0.85 | MEN1 (0.64) | MEN1KMT2AGAASLC20A2SLC20A1 | |
| SCHEMBL27179805 | 0.85 | MEN1 (0.64) | MEN1KMT2AGAASLC20A2SLC20A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MEN1 4795/4885KMT2A 2544/4885GAA 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.