Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | PCNA | P12004 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2086482 | 0.88 | ALDH1A1 (0.62) | HRH3KMT2AALDH1A1TSHRL3MBTL3 | |
| SCHEMBL3092663 | 0.80 | HRH3 (0.39) | HRH3KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL18909114 | 0.72 | HRH3 (0.51) | HRH3ALDH1A1KDM4E | |
| SCHEMBL13636248 | 0.71 | HRH3 (0.68) | HRH3KMT2AALDH1A1TSHRL3MBTL3 | |
| SCHEMBL3357953 | 0.71 | ALDH1A1 (0.43) | KMT2AALDH1A1TSHRL3MBTL3KDM4E | |
| Hydrochloric Acid SCHEMBL4378991 | 0.71 | HRH3 (0.70) | HRH3KMT2AALDH1A1TSHRL3MBTL3 | |
| SCHEMBL13928158 | 0.70 | RAMP1 (0.53) | HRH3KMT2AALDH1A1TSHRL3MBTL3 | |
| SCHEMBL13636201 | 0.69 | ALDH1A1 (0.63) | HRH3KMT2AALDH1A1TSHRL3MBTL3 | |
| SCHEMBL4377262 | 0.69 | KMT2A (0.66) | KMT2AALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL4382131 | 0.68 | KMT2A (0.68) | KMT2AALDH1A1TSHRKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249114-A1 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249114-A1 | Selected CGRP-antagonists, process for preparing them and their use as pharmaceutical compositions | CALCRL, CALCR, CALCA | HRH3 229/4885KMT2A 4658/4885ALDH1A1 1335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.