Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.64 |
| ▸ | MEN1 | O00255 | 9/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 8/20 | 0.61 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 5/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | RORC | P51449 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179417 | 1.00 | KMT2A (0.64) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10187017 | 0.85 | NR3C1 (0.81) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30926728 | 0.84 | SMN1; SMN2 (0.74) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27179715 | 0.84 | SMN1; SMN2 (0.74) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL662400 | 0.83 | L3MBTL1 (0.70) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL29978195 | 0.83 | L3MBTL1 (0.70) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL30926609 | 0.82 | KMT2A (0.70) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27180717 | 0.82 | KMT2A (0.70) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL665117 | 0.82 | MAPT (0.75) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL664662 | 0.79 | RORC (0.64) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | KMT2A 2544/4885MEN1 4795/4885ALDH1A1 1085/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.