Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 8/20 | 0.65 |
| ▸ | RXFP2 | Q8WXD0 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SLC20A2 | Q08357 | 1/20 | 0.53 |
| ▸ | SLC20A1 | Q8WUM9 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | TOP1 | P11387 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179950 | 1.00 | RXFP1 (0.65) | RXFP1RXFP2KMT2AMEN1GAA | |
| SCHEMBL7128448 | 0.84 | MEN1 (0.76) | RXFP1KMT2AMEN1GAALMNA | |
| SCHEMBL30926577 | 0.84 | MEN1 (0.76) | RXFP1KMT2AMEN1GAALMNA | |
| SCHEMBL28665241 | 0.83 | RXFP1 (0.76) | RXFP1RXFP2MAPTNPC1RAB9A | |
| SCHEMBL27181165 | 0.83 | MEN1 (0.68) | RXFP1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL30926819 | 0.83 | MEN1 (0.68) | RXFP1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL28454669 | 0.82 | MEN1 (0.64) | RXFP1KMT2AMEN1GAALMNA | |
| SCHEMBL23200355 | 0.82 | MEN1 (0.67) | RXFP1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL7120286 | 0.82 | SLC20A2 (0.74) | RXFP1KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL30926890 | 0.82 | MEN1 (0.67) | RXFP1KMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | RXFP1 3556/4885RXFP2 3504/4885KMT2A 2544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.