Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.77 |
| ▸ | MEN1 | O00255 | 2/20 | 0.77 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.57 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27179645 | 1.00 | MAPT (0.77) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27180778 | 0.84 | MAPK1 (0.62) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27181372 | 0.82 | L3MBTL1 (0.59) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27181168 | 0.82 | MAPK1 (0.58) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL30926486 | 0.81 | MAPK1 (0.63) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27179761 | 0.81 | MAPK1 (0.63) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL30926929 | 0.81 | LMNA (0.76) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL27180161 | 0.81 | LMNA (0.76) | MAPTKMT2AMEN1MAPK1ALDH1A1 | |
| SCHEMBL833815 | 0.80 | SMN1; SMN2 (0.65) | MAPTKMT2AMEN1MAPK1HTT | |
| SCHEMBL30926499 | 0.78 | LMNA (0.76) | MAPTKMT2AMEN1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | TEXAS CROP SCIENCE, INC. | 2024-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240099300-A1 | SULFONAMIDE APYRASE INHIBITORS | APEH, ARSA, DNPEP | MAPT 4236/4885KMT2A 2544/4885MEN1 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.