SCHEMBL30927166

SCHEMBL30927166

Brc1c(Br)c(Br)c2c(c1Br)Oc1ccccc1O2

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AHR P35869 8/20 0.50
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
ALOX5 P09917 1/20 0.35
NTSR1 P30989 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4374579 1.00 AHR (0.50) AHRMAOAMAOBALOX5NTSR1
SCHEMBL20990560 0.84 AHR (0.46) AHRMAOAMAOBALOX5NTSR1
SCHEMBL5587873 0.82 AHR (0.44) AHRMAOAMAOBALOX5NTSR1
SCHEMBL22137847 0.78 AHR (0.50) AHRMAOAMAOBALOX5NTSR1
SCHEMBL6255703 0.77 AHR (0.36) AHR
SCHEMBL3037003 0.76 AHR (0.55) AHRMAOAMAOBALOX5ABCG2
SCHEMBL6233357 0.74 CYP1A1 (0.39) AHRALDH1A1
SCHEMBL3722852 0.74 ATM (0.34) AHRMAOAMAOB
SCHEMBL19056391 0.74 AHR (0.46) AHRMAOAMAOBALOX5NTSR1
SCHEMBL3257583 0.74 AHR (0.48) AHRMAOAMAOBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118209659-A Analysis method of brominated dioxin in environmental sample based on GC-MS/MS 北京航空航天大学 2024-06-18 CN disclosed