SCHEMBL4374579

SCHEMBL4374579

Brc1c(Br)c(Br)c2c(c1Br)Oc1ccccc1O2

nearest known ligand 0.50

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AHR P35869 8/20 0.50
MAOA P21397 2/20 0.35
MAOB P27338 2/20 0.35
ALOX5 P09917 1/20 0.35
NTSR1 P30989 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
ABCG2 Q9UNQ0 1/20 0.33
ITGB2 P05107 1/20 0.33
ICAM1 P05362 1/20 0.33
ITGAL P20701 1/20 0.33
TSHR P16473 1/20 0.32
ALDH1A1 P00352 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30927166 1.00 AHR (0.50) AHRMAOAMAOBALOX5NTSR1
SCHEMBL20990560 0.84 AHR (0.46) AHRMAOAMAOBALOX5NTSR1
SCHEMBL5587873 0.82 AHR (0.44) AHRMAOAMAOBALOX5NTSR1
SCHEMBL22137847 0.78 AHR (0.50) AHRMAOAMAOBALOX5NTSR1
SCHEMBL6255703 0.77 AHR (0.36) AHR
SCHEMBL3037003 0.76 AHR (0.55) AHRMAOAMAOBALOX5ABCG2
SCHEMBL6233357 0.74 CYP1A1 (0.39) AHRALDH1A1
SCHEMBL3722852 0.74 ATM (0.34) AHRMAOAMAOB
SCHEMBL19056391 0.74 AHR (0.46) AHRMAOAMAOBALOX5NTSR1
SCHEMBL3257583 0.74 AHR (0.48) AHRMAOAMAOBALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118006104-A Halogen-free flame-retardant polycarbonate material and preparation method thereof 上海长伟锦磁工程塑料有限公司 2024-05-10 CN disclosed
CN-114539754-B Weather-resistant halogen-free flame-retardant bio-based polycarbonate material and preparation method thereof 上海长伟锦磁工程塑料有限公司 2023-11-14 CN disclosed
CN-110818652-B Organic luminescent material containing aryl ester derivative, preparation method and application thereof 上海和辉光电股份有限公司 2023-08-22 CN disclosed
CN-116478520-A Low-dielectric halogen-free flame-retardant weather-resistant reinforced polycarbonate material and preparation method thereof 上海长伟锦磁工程塑料有限公司 2023-07-25 CN disclosed
CN-112708253-B Sound-insulating antistatic halogen-free flame-retardant polycarbonate composite material and preparation method thereof 上海长伟锦磁工程塑料有限公司 2023-07-18 CN disclosed
CN-112538252-B Transparent hydrolysis-resistant weather-resistant halogen-free flame-retardant polycarbonate composite material 上海长伟锦磁工程塑料有限公司 2023-06-13 CN disclosed
CN-114539754-A Weather-proof halogen-free flame-retardant bio-based polycarbonate material and preparation method thereof 上海长伟锦磁工程塑料有限公司 2022-05-27 CN disclosed
CN-111073248-B Hydrolysis-resistant, illumination-resistant and low-temperature-resistant halogen-free flame-retardant polycarbonate composite material and preparation method thereof 上海长伟锦磁工程塑料有限公司 2021-12-03 CN disclosed
CN-112538252-A Transparent hydrolysis-resistant weather-resistant halogen-free flame-retardant polycarbonate composite material 上海长伟锦磁工程塑料有限公司 2021-03-23 CN disclosed
CN-112409572-A Phosphorus-containing flame-retardant low-thermal-expansion-coefficient epoxy resin, preparation method thereof, related intermediate product and application 苏州巨峰新材料科技有限公司 2021-02-26 CN disclosed
CN-103122010-A Novel phosphorus monofunctional, bifunctional and multifunctional phenols and derivatives thereof and preparation method thereof NAT UNIV CHUNG HSING 2013-05-29 CN disclosed
EP-2546258-A1 Novel phosphorus-containing compounds and their preparing process and use Chang Chun Plastics Co., Ltd. (TW) 2013-01-16 EP disclosed
US-20130012668-A1 MONOFUNCTIONAL, BIFUNCTIONAL, AND MULTIFUNCTIONAL PHOSPHINATED PHENOLS AND THEIR DERIVATIVES AND PREPARATION METHOD THEREOF NATIONAL CHUNG HSING UNIVERSITY (TW) 2013-01-10 US disclosed
CN-101560226-B Novel phosphorus-based compound, and production method and use thereof CHANGCHUN PLASTICS CO LTD 2013-01-09 CN disclosed
US-8222441-B2 Phosphorus-containing compounds and their preparing process and use CHANG CHUN PLASTICS CO., LTD. (TW) 2012-07-17 US disclosed
CN-102093688-A High-performance halogen-free flame-retardant PC (polycarbonate)/ABS (acrylonitrile-butadiene-styrene) alloy and preparation method thereof UNIV CHANGZHOU 2011-06-15 CN disclosed
EP-2116549-A2 Novel phosphorus-containing compounds and their preparing process and use Chang Chun Plastics Co., Ltd. (TW) 2009-11-11 EP disclosed
CN-101560226-A Novel phosphorus-based compound, and production method and use thereof CHANG CHUN PLASTIC CO LTD (CN) 2009-10-21 CN disclosed
US-20090258997-A1 Novel phosphorus-containing compounds and their preparing process and use CHANG CHUN PLASTICS CO., LTD. 2009-10-15 US disclosed
CN-1182198-C Reaction-type environmentally friendly flame-retarding high-lustre polyphenylene-ether compound and its preparing process 上海金发科技发展有限公司 2004-12-29 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090258997-A1 Novel phosphorus-containing compounds and their preparing process and use POLR2A, POLR2B, PRXL2A AHR 4139/4885MAOA 3005/4885MAOB 2368/4885
US-20130012668-A1 MONOFUNCTIONAL, BIFUNCTIONAL, AND MULTIFUNCTIONAL PHOSPHINATED PHENOLS AND THEIR DERIVATIVES AND PREPARATION METHOD THEREOF PHOSPHO1, PLCG2, PLCB3 AHR 1107/4885MAOA 587/4885MAOB 432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.