SCHEMBL6233357

SCHEMBL6233357

CCCc1c(Br)c(Br)c2c(c1CCC)Oc1ccccc1O2

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP1A1 P04798 2/20 0.39
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 1/20 0.37
AHR P35869 4/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6253061 0.90 CYP1A1 (0.49) CYP1A1ALDH1A1KDM4EHPGDAHR
SCHEMBL6255703 0.82 AHR (0.36) CYP1A1AHR
SCHEMBL5587181 0.77 CYP1A1 (0.41) CYP1A1ALDH1A1KDM4EGAAHPGD
SCHEMBL6256853 0.76 AHR (0.57) CYP1A1ALDH1A1KDM4EGAAHPGD
SCHEMBL5590203 0.75 CA1 (0.30)
SCHEMBL6252702 0.75 ALDH1A1 (0.39) CYP1A1ALDH1A1KDM4EGAAHPGD
SCHEMBL4374579 0.74 AHR (0.50) ALDH1A1AHR
SCHEMBL30927166 0.74 AHR (0.50) ALDH1A1AHR
SCHEMBL5588453 0.68
SCHEMBL5588428 0.68 CA1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP disclosed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO disclosed