SCHEMBL5587873

SCHEMBL5587873

Oc1c(O)c(Br)c2c(c1Br)Oc1ccccc1O2

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AHR P35869 7/20 0.44
ALOX15 P16050 2/20 0.35
ALOX12 P18054 2/20 0.35
PRMT1 Q99873 1/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
CA4 P22748 2/20 0.35
CA6 P23280 2/20 0.35
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
CRHBP P24387 1/20 0.32
CRHR2 Q13324 1/20 0.32
NTSR1 P30989 1/20 0.31
GPR55 Q9Y2T6 1/20 0.31
POLB P06746 1/20 0.31
ALOX5 P09917 1/20 0.31
DRD4 P21917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30927166 0.82 AHR (0.50) AHRMAOAMAOBNTSR1GPR55
SCHEMBL4374579 0.82 AHR (0.50) AHRMAOAMAOBNTSR1GPR55
SCHEMBL5588050 0.81 ALOX15 (0.41) AHRALOX15ALOX12PRMT1CA1
SCHEMBL5693570 0.80 AHR (0.42) AHRALOX15ALOX12PRMT1
SCHEMBL9530690 0.79 AHR (0.57) AHRALOX15CA1CA2CA4
SCHEMBL20990560 0.78 AHR (0.46) AHRMAOAMAOBNTSR1GPR55
SCHEMBL5586769 0.74 ALOX15 (0.42) AHRALOX15ALOX12PRMT1CA1
SCHEMBL22137847 0.72 AHR (0.50) AHRMAOAMAOBNTSR1GPR55
SCHEMBL5588066 0.71 AHR (0.70) AHRMAOAMAOBNTSR1GPR55
SCHEMBL5590092 0.71 AHR (0.44) AHRMAOAMAOBNTSR1GPR55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US disclosed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP disclosed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 AHR 1434/4885ALOX15 76/4885ALOX12 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.