SCHEMBL30928286

SCHEMBL30928286

[C-]#[N+]C([N+]#[C-])S(=O)(=O)c1ccc(CCC=C)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.34
CA2 P00918 13/20 0.33
CA1 P00915 8/20 0.33
CA9 Q16790 6/20 0.33
CA12 O43570 5/20 0.33
CA7 P43166 4/20 0.33
CA4 P22748 3/20 0.33
CA5A P35218 3/20 0.33
CA5B Q9Y2D0 3/20 0.33
CA6 P23280 2/20 0.33
CA14 Q9ULX7 2/20 0.33
F2 P00734 2/20 0.33
TMPRSS4 Q9NRS4 2/20 0.33
TP53 P04637 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
TSHR P16473 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.31
HTR6 P50406 1/20 0.31
PSIP1 O75475 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1698660 0.75 CA2 (0.60) CA2CA1CA9CA12CA7
SCHEMBL2467283 0.75 TDP1 (0.52) POLBCA2CA1CA9CA12
SCHEMBL29129905 0.75 ALDH1A1 (0.40) POLBCA2CA1CA9CA12
SCHEMBL9004469 0.73 GFER (0.36) CA2TP53TSHRSMN1; SMN2
SCHEMBL6285109 0.71 GFER (0.41) TP53TSHRSMN1; SMN2
SCHEMBL6175569 0.69 GAA (0.50) CA2CA1CA9CA12CA7
SCHEMBL7789024 0.69 CYP2A6 (0.39) SMN1; SMN2
SCHEMBL5543474 0.68 THRB (0.34) TP53TSHRSMN1; SMN2
SCHEMBL8854472 0.67 HRH3 (0.41) TP53TSHRSMN1; SMN2
Sulfuric Acid SCHEMBL15238309 0.66 MAPT (0.52) POLBCA2CA1CA9SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118164900-A Multifunctional pyridine compound and preparation method and application thereof 昆明理工大学 2024-06-11 CN claimed
CN-118164900-B Multifunctional pyridine compound and preparation method and application thereof 昆明理工大学 2025-10-31 CN disclosed
CN-118164900-A Multifunctional pyridine compound and preparation method and application thereof 昆明理工大学 2024-06-11 CN disclosed
CN-118164900-A Multifunctional pyridine compound and preparation method and application thereof 昆明理工大学 2024-06-11 CN disclosed