Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 11/20 | 0.37 |
| ▸ | FEN1 | P39748 | 11/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8112909 | 0.80 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9MAPK1SMN1; SMN2 | |
| SCHEMBL8105849 | 0.79 | ALDH1A1 (0.36) | ALDH1A1CYP3A4CYP2C9MAPK1ALOX5AP | |
| SCHEMBL9367060 | 0.74 | GAA (0.43) | ALDH1A1SMN1; SMN2MAPTLMNAKDM4E | |
| SCHEMBL8114335 | 0.74 | ALDH1A1 (0.35) | ALDH1A1CYP3A4CYP2C9MAPK1SMN1; SMN2 | |
| SCHEMBL31017736 | 0.71 | HSD11B1 (0.49) | ALDH1A1HSD11B1MAPTLMNAKDM4E | |
| SCHEMBL31017728 | 0.70 | SCN1A (0.47) | CYP2C9 | |
| SCHEMBL31017734 | 0.69 | SCN8A (0.55) | CYP2C9 | |
| SCHEMBL16377391 | 0.69 | ALDH1A1 (0.46) | ALDH1A1CYP3A4CYP2C9MAPK1ALOX5AP | |
| SCHEMBL8112810 | 0.69 | SLC40A1 (0.49) | ALDH1A1HSD11B1SMN1; SMN2MAPTLMNA | |
| SCHEMBL21963333 | 0.68 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2C9MAPK1ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240182460-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PETRA PHARMA CORPORATION | 2024-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240182460-A1 | ALLOSTERIC CHROMENONE INHIBITORS OF PHOSPHOINOSITIDE 3-KINASE (PI3K) FOR THE TREATMENT OF DISEASE | PIK3CA, PIK3R4, PIK3R5 | ALDH1A1 3403/4885CYP3A4 629/4885CYP2C9 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.