Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.43 |
| ▸ | LGMN | Q99538 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.42 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.42 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928908 | 0.90 | PTGER4 (0.46) | TDP1KMT2AALDH1A1MEN1RECQL | |
| SCHEMBL7821971 | 0.80 | KDM4E (0.53) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL31122794 | 0.79 | KMT2A (0.42) | KMT2AADORA3LGMNADORA2AADORA2B | |
| SCHEMBL30928907 | 0.78 | ALDH1A1 (0.49) | TDP1KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL30928929 | 0.76 | GRN (0.46) | KMT2AADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL31122799 | 0.75 | MAPT (0.44) | KMT2AADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL31122820 | 0.74 | ADORA3 (0.41) | KMT2AADORA3LGMNADORA2AADORA2B | |
| SCHEMBL31122798 | 0.74 | ADORA3 (0.41) | KMT2AADORA3LGMNADORA2AADORA2B | |
| SCHEMBL31122808 | 0.74 | GSK3B (0.41) | KMT2AADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL31122803 | 0.74 | ADORA3 (0.41) | KMT2AADORA3LGMNADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184594-A | Preparation method of aza-uracil compound, and compound prepared by same and application of aza-uracil compound | 杭州医学院 | 2024-06-14 | — | — | CN | disclosed |