Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928896 | 0.90 | TDP1 (0.52) | KMT2ATDP1MEN1ALDH1A1RECQL | |
| SCHEMBL30928917 | 0.81 | GRN (0.47) | PTGER4KMT2ATDP1MEN1POLB | |
| SCHEMBL30928900 | 0.80 | ALDH1A1 (0.52) | PTGER4KMT2ATDP1MEN1POLB | |
| SCHEMBL30928928 | 0.74 | GCGR (0.46) | PTGER4KMT2AALDH1A1SMN1; SMN2IDO1 | |
| SCHEMBL30928893 | 0.73 | PDE1A (0.42) | PTGER4KMT2ATDP1MEN1POLB | |
| SCHEMBL1007634 | 0.72 | PTGER4 (0.44) | PTGER4KMT2ATDP1MEN1POLB | |
| SCHEMBL7821971 | 0.71 | KDM4E (0.53) | KMT2AMEN1POLBKDM4EALDH1A1 | |
| SCHEMBL31122794 | 0.71 | KMT2A (0.42) | KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL30928907 | 0.70 | ALDH1A1 (0.49) | KMT2ATDP1MEN1USP2ALDH1A1 | |
| SCHEMBL3556560 | 0.68 | HDAC1 (0.67) | THRBMMP13SLC22A8HDAC1HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184594-A | Preparation method of aza-uracil compound, and compound prepared by same and application of aza-uracil compound | 杭州医学院 | 2024-06-14 | — | — | CN | disclosed |