Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30928915 | 0.85 | CYP1A2 (0.54) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928913 | 0.84 | ALDH1A1 (0.46) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928916 | 0.83 | ALDH1A1 (0.53) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928924 | 0.83 | ALDH1A1 (0.52) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928898 | 0.83 | ALDH1A1 (0.67) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928909 | 0.82 | TDP2 (0.55) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928890 | 0.80 | ALDH1A1 (0.65) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928899 | 0.80 | ADORA2A (0.55) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL30928897 | 0.80 | ALDH1A1 (0.49) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 | |
| SCHEMBL30928912 | 0.79 | ALDH1A1 (0.57) | CFTRALDH1A1NPSR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118184594-A | Preparation method of aza-uracil compound, and compound prepared by same and application of aza-uracil compound | 杭州医学院 | 2024-06-14 | — | — | CN | disclosed |