Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734214 | 0.75 | HDAC1 (0.53) | CMA1GAAHDAC1GSK3AGSK3B | |
| SCHEMBL17360667 | 0.75 | CMA1 (0.59) | CMA1GAAGSK3AGSK3BHDAC6 | |
| SCHEMBL14047401 | 0.74 | ALDH1A1 (0.57) | GRM2CHRM5ALDH1A1LMNA | |
| SCHEMBL15858013 | 0.74 | GAA (0.54) | CMA1GAAHDAC1GSK3AGSK3B | |
| SCHEMBL21382559 | 0.72 | GAA (0.49) | CMA1GAAHDAC1GSK3AGSK3B | |
| SCHEMBL11432095 | 0.72 | GAA (0.68) | CMA1GAAGSK3AGSK3BSIGMAR1 | |
| SCHEMBL26114501 | 0.72 | CMA1 (0.56) | CMA1GAAHDAC1GSK3AGSK3B | |
| SCHEMBL27721848 | 0.72 | CMA1 (0.51) | CMA1GAAGSK3AGSK3BHDAC6 | |
| SCHEMBL30503756 | 0.72 | HDAC6 (0.56) | CMA1GAAHDAC1GSK3AGSK3B | |
| SCHEMBL15858043 | 0.71 | SIGMAR1 (0.51) | CMA1GAASIGMAR1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615832-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | Bristol-Myers Squibb Company (US) | 2025-09-17 | — | — | EP | disclosed |
| CN-120152968-A | Substituted heterocyclic compounds | 百时美施贵宝公司 | 2025-06-13 | — | — | CN | disclosed |
| WO-2024102683-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-05-16 | — | — | WO | disclosed |