Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807732 | 0.77 | ADRA2C (0.41) | USP2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL22770859 | 0.76 | USP2 (0.40) | USP2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL14168524 | 0.76 | USP2 (0.40) | USP2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL29604163 | 0.76 | USP2 (0.40) | USP2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL8259789 | 0.75 | HRH3 (0.40) | USP2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL5782684 | 0.75 | USP2 (0.39) | USP2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL17277337 | 0.74 | LMNA (0.38) | USP2ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL632880 | 0.72 | GAA (0.42) | KMT2A | |
| SCHEMBL3954454 | 0.71 | — | — | |
| SCHEMBL523804 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118201916-A | Piperazinylsulfonylaryl compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118201916-A | Piperazinylsulfonylaryl compounds for the treatment of bacterial infections | 豪夫迈·罗氏有限公司 | 2024-06-14 | — | — | CN | disclosed |