Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | CES1 | P23141 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9456923 | 1.00 | KMT2A (0.41) | KMT2AKEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9456919 | 1.00 | KMT2A (0.41) | KMT2AKEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL9457024 | 1.00 | KMT2A (0.41) | KMT2AKEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL254515 | 0.84 | ALDH1A1 (0.37) | KMT2AALDH1A1SMN1; SMN2GAAMEN1 | |
| SCHEMBL7753032 | 0.83 | EGLN1 (0.35) | KMT2AKEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7757191 | 0.83 | EGLN1 (0.35) | KMT2AKEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL7753034 | 0.83 | EGLN1 (0.35) | KMT2AKEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL20154868 | 0.82 | ALDH1A1 (0.35) | KMT2AKEAP1NFE2L2ALDH1A1SMN1; SMN2 | |
| SCHEMBL11361617 | 0.82 | CA2 (0.43) | KMT2AALDH1A1MEN1RAB9ANPC1 | |
| SCHEMBL30828026 | 0.81 | CES1 (0.39) | KMT2AKEAP1ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117778339-A | Sulfoxide reductase mutant and application thereof in preparation of chiral sulfoxide and sulfinyl ester | 遵义医科大学 | 2024-03-29 | — | — | CN | disclosed |