Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.32 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753032 | 1.00 | EGLN1 (0.35) | EGLN1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7757191 | 1.00 | EGLN1 (0.35) | EGLN1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL7759008 | 0.84 | TDP1 (0.36) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL9457024 | 0.83 | KMT2A (0.41) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL9456923 | 0.83 | KMT2A (0.41) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL9456919 | 0.83 | KMT2A (0.41) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL30929941 | 0.83 | KMT2A (0.41) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL7759020 | 0.82 | MMP9 (0.33) | EGLN1KMT2ANPC1RAB9AMEN1 | |
| SCHEMBL9843695 | 0.78 | ALDH1A1 (0.33) | KMT2ANPC1RAB9AMEN1GAA | |
| SCHEMBL9843698 | 0.78 | ALDH1A1 (0.33) | KMT2ANPC1RAB9AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805800-B1 | METHOD FOR PREPARING (+)COMPACTIN AND (+)MEVINOLIN ANALOG COMPOUNDS HAVING A BETA-HYDROXY-DELTA-LACTONE GROUPING | OREAL (FR) | 2001-03-14 | — | — | EP | claimed |
| EP-0805800-A1 | METHOD FOR PREPARING (+)COMPACTIN AND (+)MEVINOLIN ANALOG COMPOUNDS HAVING A BETA-HYDROXY-DELTA-LACTONE GROUPING | L'OREAL (FR) | 1997-11-12 | — | — | EP | claimed |
| WO-1997019917-A1 | METHOD FOR PREPARING (+)COMPACTIN AND (+)MEVINOLIN ANALOG COMPOUNDS HAVING A β-HYDROXY-δ-LACTONE GROUPING | L'OREAL (FR) | 1997-06-05 | — | — | WO | claimed |
| US-6278001-B1 | REACTING TRI-ANION OF ALKYL 3,5-DIOXOHEXANOATE COMPOUND WITH MENTHYL-P-TOLUENESULPHINATE COMPOUND; REDUCTION TO FORM HYDROXYL GROUPS; PROTECTING HYDROXYL GROUPS; REDUCTION OF SULPHOXIDE GROUP; FORMING ALDEHYDE GROUP; WITTIG REACTION | L'ORÉAL (FR) | 2001-08-21 | — | — | US | disclosed |
| EP-0805800-B1 | METHOD FOR PREPARING (+)COMPACTIN AND (+)MEVINOLIN ANALOG COMPOUNDS HAVING A BETA-HYDROXY-DELTA-LACTONE GROUPING | OREAL (FR) | 2001-03-14 | — | — | EP | disclosed |
| EP-0805800-A1 | METHOD FOR PREPARING (+)COMPACTIN AND (+)MEVINOLIN ANALOG COMPOUNDS HAVING A BETA-HYDROXY-DELTA-LACTONE GROUPING | L'OREAL (FR) | 1997-11-12 | — | — | EP | disclosed |
| WO-1997019917-A1 | METHOD FOR PREPARING (+)COMPACTIN AND (+)MEVINOLIN ANALOG COMPOUNDS HAVING A β-HYDROXY-δ-LACTONE GROUPING | L'OREAL (FR) | 1997-06-05 | — | — | WO | disclosed |