Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 8/20 | 0.44 |
| ▸ | NOS3 | P29474 | 7/20 | 0.44 |
| ▸ | NOS1 | P29475 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1143077 | 1.00 | NOS2 (0.44) | NOS2NOS3NOS1LMNABACE1 | |
| SCHEMBL29174222 | 0.84 | KDM4E (0.46) | NOS2NOS3NOS1LMNAALDH1A1 | |
| SCHEMBL31256275 | 0.77 | LMNA (0.41) | NOS2NOS3NOS1LMNABACE1 | |
| SCHEMBL14853216 | 0.75 | KDM4E (0.41) | NOS2NOS3NOS1LMNAMAPK1 | |
| SCHEMBL3673476 | 0.75 | NOS2 (0.48) | NOS2NOS3NOS1BACE1PRMT5 | |
| SCHEMBL5758060 | 0.75 | NOS2 (0.48) | NOS2NOS3NOS1BACE1PRMT5 | |
| SCHEMBL24722955 | 0.74 | NOS2 (0.42) | NOS2NOS3NOS1BACE1REN | |
| SCHEMBL18369638 | 0.73 | BACE1 (0.47) | NOS2NOS3NOS1LMNABACE1 | |
| SCHEMBL4246844 | 0.71 | LMNA (0.34) | LMNA | |
| SCHEMBL21632441 | 0.71 | NOS2 (0.44) | NOS2NOS3NOS1BACE1PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047654-A | Process for preparing aryl halides starting from aromatic amines | 黑龙江立科新材料有限公司 | 2024-05-17 | — | — | CN | disclosed |