Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ERN1 | O75460 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | CFTR | P13569 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30930748 | 0.82 | MAPT (0.45) | POLBMAPTPDE4APDE4BPDE4C | |
| SCHEMBL30930754 | 0.79 | SIRT6 (0.50) | SIRT6POLBMAPTALDH1A1 | |
| SCHEMBL29282830 | 0.79 | SIRT6 (0.50) | SIRT6POLBMAPTALDH1A1 | |
| SCHEMBL520107 | 0.77 | SIRT6 (0.61) | SIRT6POLBMAPTERN1KDM4E | |
| SCHEMBL30930735 | 0.76 | SIRT6 (0.49) | SIRT6POLBMAPTERN1KDM4E | |
| SCHEMBL29282820 | 0.73 | NOTUM (0.47) | POLBMAPTNPC1RAB9AHPGD | |
| SCHEMBL30930760 | 0.73 | NOTUM (0.47) | POLBMAPTNPC1RAB9AHPGD | |
| SCHEMBL15880409 | 0.72 | ALDH1A1 (0.58) | SIRT6POLBMAPTKDM4EALDH1A1 | |
| SCHEMBL29282823 | 0.71 | POLB (0.43) | POLBMAPTALDH1A1LMNANPC1 | |
| SCHEMBL520898 | 0.70 | ALDH1A1 (0.66) | POLBMAPTALDH1A1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118047779-B | Dihydropteridinone derivatives containing benzobisheteroaryl and use thereof | 沈阳药科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-118047779-A | Dihydropteridinone derivatives containing benzobisheteroaryl and use thereof | 沈阳药科大学 | 2024-05-17 | — | — | CN | disclosed |