Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 11/20 | 0.47 |
| ▸ | DRD4 | P21917 | 11/20 | 0.47 |
| ▸ | DRD3 | P35462 | 11/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29282830 | 1.00 | SIRT6 (0.50) | SIRT6POLBDRD2DRD4DRD3 | |
| SCHEMBL30930756 | 0.82 | DRD2 (0.48) | DRD2DRD4DRD3MAPTALDH1A1 | |
| SCHEMBL38657531 | 0.81 | ALDH1A1 (0.60) | SIRT6POLBMAPTALDH1A1L3MBTL1 | |
| SCHEMBL30930760 | 0.80 | NOTUM (0.47) | POLBDRD2DRD4DRD3MAPT | |
| SCHEMBL29282823 | 0.80 | POLB (0.43) | POLBDRD2DRD4DRD3MAPT | |
| SCHEMBL29282820 | 0.80 | NOTUM (0.47) | POLBDRD2DRD4DRD3MAPT | |
| SCHEMBL30930737 | 0.79 | SIRT6 (0.49) | SIRT6POLBMAPTALDH1A1 | |
| SCHEMBL8576630 | 0.78 | ALDH1A1 (0.66) | POLBMAPTALDH1A1HTTL3MBTL1 | |
| SCHEMBL38657436 | 0.78 | SIRT6 (0.50) | SIRT6POLBMAPTALDH1A1HTT | |
| SCHEMBL38657597 | 0.78 | SIRT6 (0.50) | SIRT6POLBMAPTALDH1A1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122036715-A | 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof | 盐城工业职业技术学院 | 2026-05-15 | — | — | CN | disclosed |
| CN-118047779-B | Dihydropteridinone derivatives containing benzobisheteroaryl and use thereof | 沈阳药科大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-118047779-A | Dihydropteridinone derivatives containing benzobisheteroaryl and use thereof | 沈阳药科大学 | 2024-05-17 | — | — | CN | disclosed |