Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.33 |
| ▸ | MPL | P40238 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23044963 | 1.00 | PDE10A (0.38) | PDE10AMETAP2HCRTR1HCRTR2PDE2A | |
| SCHEMBL30932107 | 0.82 | HCRTR1 (0.33) | PDE10AMETAP2HCRTR1HCRTR2EIF2AK4 | |
| SCHEMBL23044952 | 0.82 | HCRTR1 (0.33) | PDE10AMETAP2HCRTR1HCRTR2EIF2AK4 | |
| SCHEMBL30932100 | 0.81 | CNR2 (0.39) | PDE10APIM1 | |
| SCHEMBL23044954 | 0.80 | HCRTR1 (0.34) | PDE10AHCRTR1HCRTR2ABL1PIM1 | |
| SCHEMBL23057529 | 0.73 | ABL1 (0.37) | HCRTR1HCRTR2ABL1MPL | |
| SCHEMBL30932106 | 0.73 | ABL1 (0.37) | HCRTR1HCRTR2ABL1MPL | |
| SCHEMBL22153186 | 0.72 | PDE10A (0.35) | PDE10AMETAP2PIM1 | |
| SCHEMBL17537343 | 0.68 | PDE2A (0.35) | PDE10APDE2AMPL | |
| SCHEMBL18420934 | 0.67 | KMT2A (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |