Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 3/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.32 |
| ▸ | TTR | P02766 | 5/20 | 0.31 |
| ▸ | RBP4 | P02753 | 5/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932098 | 0.80 | PDE10A (0.38) | HCRTR1HCRTR2PDE10ARBP4PIM1 | |
| SCHEMBL23044963 | 0.80 | PDE10A (0.38) | HCRTR1HCRTR2PDE10ARBP4PIM1 | |
| SCHEMBL30932107 | 0.79 | HCRTR1 (0.33) | HCRTR1HCRTR2PDE10A | |
| SCHEMBL23044952 | 0.79 | HCRTR1 (0.33) | HCRTR1HCRTR2PDE10A | |
| SCHEMBL23044980 | 0.78 | MCHR1 (0.35) | HCRTR1HCRTR2MCHR1ABL1 | |
| SCHEMBL30932100 | 0.73 | CNR2 (0.39) | PDE10ACNR2MCHR1PIM1 | |
| SCHEMBL28537629 | 0.70 | HCRTR1 (0.32) | HCRTR1HCRTR2CNR2MCHR1KDM2B | |
| SCHEMBL28530473 | 0.65 | SLC6A2 (0.32) | — | |
| SCHEMBL22129474 | 0.64 | PDE10A (0.46) | PDE10ACNR2CHRM1 | |
| SCHEMBL29227988 | 0.64 | CNR2 (0.32) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| CN-112409333-A | Phenylpyrrolidines | 湖北生物医药产业技术研究院有限公司 | 2021-02-26 | — | — | CN | disclosed |