Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 12/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | CLK2 | P49760 | 1/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.34 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932106 | 1.00 | ABL1 (0.37) | ABL1SOS1TACR1TACR3HCRTR1 | |
| SCHEMBL23044984 | 0.82 | MCHR1 (0.33) | HCRTR1HCRTR2MCHR1SMO | |
| SCHEMBL30932101 | 0.81 | AR (0.40) | SOS1MCHR1 | |
| SCHEMBL23044980 | 0.80 | MCHR1 (0.35) | ABL1HCRTR1HCRTR2MCHR1SMO | |
| SCHEMBL23044963 | 0.73 | PDE10A (0.38) | ABL1HCRTR1HCRTR2MPL | |
| SCHEMBL30932098 | 0.73 | PDE10A (0.38) | ABL1HCRTR1HCRTR2MPL | |
| SCHEMBL13073944 | 0.70 | UHRF1 (0.42) | — | |
| SCHEMBL22129386 | 0.70 | SMO (0.45) | SOS1LRRK2MCHR1SMO | |
| SCHEMBL29929479 | 0.70 | SMO (0.45) | SOS1LRRK2MCHR1SMO | |
| SCHEMBL19795270 | 0.67 | SCN5A (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112409333-B | Phenylpyrrolidine compounds | 武汉人福创新药物研发中心有限公司 | 2024-06-14 | — | — | CN | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |