Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 2/20 | 0.33 |
| ▸ | PROKR1 | Q8TCW9 | 2/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.32 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.31 |
| ▸ | ACACB | O00763 | 2/20 | 0.31 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30932107 | 1.00 | HCRTR1 (0.33) | HCRTR1HCRTR2FPR2PROKR1PDE10A | |
| SCHEMBL23044963 | 0.82 | PDE10A (0.38) | HCRTR1HCRTR2PDE10AEIF2AK4METAP2 | |
| SCHEMBL30932098 | 0.82 | PDE10A (0.38) | HCRTR1HCRTR2PDE10AEIF2AK4METAP2 | |
| SCHEMBL23044954 | 0.79 | HCRTR1 (0.34) | HCRTR1HCRTR2PDE10A | |
| SCHEMBL23044984 | 0.77 | MCHR1 (0.33) | HCRTR1HCRTR2FPR2PROKR1PDE10A | |
| SCHEMBL30932100 | 0.74 | CNR2 (0.39) | PDE10ACACNA2D1CACNA2D2 | |
| SCHEMBL22480003 | 0.71 | PPARD (0.43) | FPR2PROKR1NR1H2NR1H3 | |
| SCHEMBL17559324 | 0.70 | GPR119 (0.48) | PDE10AGPR119ACACB | |
| SCHEMBL2264016 | 0.67 | HTT (0.55) | KCNH2 | |
| SCHEMBL22152251 | 0.66 | GPR119 (0.49) | PDE10AGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |
| WO-2021036953-A1 | PHENYLPYRROLIDINE COMPOUND | 湖北生物医药产业技术研究院有限公司 | 2021-03-04 | — | — | WO | disclosed |