Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 16/20 | 0.61 |
| ▸ | CA2 | P00918 | 16/20 | 0.61 |
| ▸ | CA12 | O43570 | 9/20 | 0.61 |
| ▸ | CA9 | Q16790 | 9/20 | 0.61 |
| ▸ | CA4 | P22748 | 5/20 | 0.61 |
| ▸ | CA6 | P23280 | 4/20 | 0.61 |
| ▸ | CA5A | P35218 | 4/20 | 0.61 |
| ▸ | CA7 | P43166 | 4/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.61 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.61 |
| ▸ | CA3 | P07451 | 3/20 | 0.61 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.48 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554246 | 0.90 | CA1 (0.50) | CA1CA2CA12CA9CA4 | |
| SCHEMBL5012991 | 0.89 | CA1 (0.49) | CA1CA2CA12CA9CA4 | |
| SCHEMBL11552574 | 0.88 | CA1 (0.48) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6038490 | 0.87 | CA2 (0.56) | CA1CA2CA12CA9CA4 | |
| SCHEMBL11511279 | 0.84 | KDM4E (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3267605 | 0.83 | CA12 (0.56) | CA1CA2CA12CA9CA4 | |
| SCHEMBL5014186 | 0.81 | CA1 (0.70) | CA1CA2CA12CA9CA4 | |
| SCHEMBL8404547 | 0.79 | CA1 (0.42) | CA1CA2CA12CA9CA4 | |
| SCHEMBL20485787 | 0.78 | CA1 (0.50) | CA1CA2CA12CA9CA4 | |
| SCHEMBL11555026 | 0.78 | CA2 (0.47) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2974 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021054927-A2 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2021-03-25 | — | — | WO | claimed |
| US-20200048305-A1 | GLUTATHIONE-CHOLESTEROL DERIVATIVES AS BRAIN TARGETING AGENTS | SOUTH DAKOTA BOARD OF REGENTS (US) | 2020-02-13 | — | — | US | claimed |
| US-9622969-B2 | Polymer conjugated protein micelles | SOUTH DAKOTA STATE UNIV (US) | 2017-04-18 | — | — | US | claimed |
| CN-103232403-B | A kind of preparation method of nitrogen heterocyclic | ZHEJIANG CHEMPACIFIC CHEMICAL CO., LTD. (CN) | 2016-04-27 | — | — | CN | claimed |
| CN-105462285-A | Synthesis method of disperse red F3BS | JIANGSU DAOBO CHEMICAL CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-105440135-A | Anti-PD-L1 conjugates for the treatment of tumors | BODI BIOTECHNOLOGY CO LTD | 2016-03-30 | — | — | CN | claimed |
| CN-105452232-A | Process for the preparation of dronedarone and salts thereof | GILEAD SCIENCES INC | 2016-03-30 | — | — | CN | claimed |
| CN-105399751-A | BUPRENORPHINE ANALOGS | PURDUE PHARMA LP | 2016-03-16 | — | — | CN | claimed |
| CN-105392787-A | Aza-oxo-indoles for the treatment and prophylaxis of respiratory syncytial virus infection | HOFFMANN LA ROCHE | 2016-03-09 | — | — | CN | claimed |
| CN-102917590-B | Tricyclic compound and the PBK inhibitor containing described compound | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | claimed |
| CN-1200722-A | Process for purifying diphenyl ether compound | ZENECA LTD (GB) | 1998-12-02 | — | — | CN | claimed |
| CN-1196045-A | Process for nitrating diphenyl ether compounds | ZENECA LTD (GB) | 1998-10-14 | — | — | CN | claimed |
| CN-1039998-C | New isobutyl-substituted methanesulphonyl-quinolylmethoxyphenyl-cycloa lkylacetamides | BAYER AG (DE) | 1998-09-30 | — | — | CN | claimed |
| CN-1189823-A | Cyclic amidino formulations useful as nitric oxide synthase inhibitors | SEARLE & CO (US) | 1998-08-05 | — | — | CN | claimed |
| CN-1166831-A | Novel benzyl pyrimidines | HOFFMANN LA ROCHE (CH) | 1997-12-03 | — | — | CN | claimed |
| CN-1132206-A | Pyrrole derivatives | HOFFMANN LA ROCHE (CH) | 1996-10-02 | — | — | CN | claimed |
| CN-1110685-A | Nitrogen-containing spiro ring | MERCK & CO INC (US) | 1995-10-25 | — | — | CN | claimed |
| CN-1087084-A | Methylsulfonyl-quinolyl p-methoxy-phenyl-cycloalkyl ethanamide that new isobutyl-replaces | BAYER AG (DE) | 1994-05-25 | — | — | CN | claimed |
| CN-1081438-A | Imdazole derivatives and preparation method thereof and the application on therapeutics | FOURNIER IND & SANTE (FR) | 1994-02-02 | — | — | CN | claimed |
| CN-87106996-A | Quinoline compound, their preparation method and with its carcinostatic agent as the active drug component | — | 1988-06-15 | — | — | CN | claimed |