Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 15/20 | 0.50 |
| ▸ | CA2 | P00918 | 15/20 | 0.50 |
| ▸ | CA12 | O43570 | 10/20 | 0.50 |
| ▸ | CA9 | Q16790 | 10/20 | 0.50 |
| ▸ | CA4 | P22748 | 5/20 | 0.50 |
| ▸ | CA6 | P23280 | 4/20 | 0.50 |
| ▸ | CA5A | P35218 | 4/20 | 0.50 |
| ▸ | CA7 | P43166 | 4/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.50 |
| ▸ | CA3 | P07451 | 3/20 | 0.50 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.41 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Disulfamide SCHEMBL309326 | 0.90 | CA1 (0.61) | CA1CA2CA12CA9CA4 | |
| SCHEMBL5012991 | 0.84 | CA1 (0.49) | CA1CA2CA12CA9CA4 | |
| SCHEMBL11552574 | 0.83 | CA1 (0.48) | CA1CA2CA12CA9CA4 | |
| SCHEMBL6038490 | 0.82 | CA2 (0.56) | CA1CA2CA12CA9CA4 | |
| SCHEMBL3483762 | 0.79 | TSHR (0.44) | CA1CA2CA12CA9LMNA | |
| SCHEMBL11511279 | 0.79 | KDM4E (0.52) | CA1CA2CA12CA9CA4 | |
| SCHEMBL26512818 | 0.77 | TRPV4 (0.38) | CA1CA2CA12CA9L3MBTL1 | |
| SCHEMBL4426923 | 0.76 | TRPV4 (0.48) | CA1CA2CA12CA9CA4 | |
| SCHEMBL152556 | 0.75 | SOD1 (0.47) | CA1CA2CA12CA9LMNA | |
| SCHEMBL29707985 | 0.75 | SOD1 (0.47) | CA1CA2CA12CA9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161533-A | DIURETICS, SALURETICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-17 | — | — | US | disclosed |