Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 5/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933881 | 0.94 | KDM4E (0.46) | KDM4EPKMSTSGPR119TGFBR1 | |
| SCHEMBL30933838 | 0.77 | KDM4E (0.48) | KDM4EPKMSTSGPR119TP53 | |
| SCHEMBL4326217 | 0.76 | KDM4E (0.60) | KDM4EPKMSTSGPR119TP53 | |
| SCHEMBL30933710 | 0.76 | KDM4E (0.48) | KDM4EPKMSTSGPR119TP53 | |
| SCHEMBL30933751 | 0.76 | KDM4E (0.48) | KDM4EPKMSTSGPR119TP53 | |
| SCHEMBL3979358 | 0.76 | KDM4E (0.57) | KDM4EPKMSTSGPR119TGFBR1 | |
| SCHEMBL30933770 | 0.75 | KDM4E (0.47) | KDM4EPKMSTSGPR119TP53 | |
| SCHEMBL30933771 | 0.75 | PKM (0.47) | KDM4EPKMSTSGPR119TP53 | |
| SCHEMBL4328635 | 0.75 | STS (0.56) | KDM4EPKMSTSMAPK8 | |
| SCHEMBL30933793 | 0.74 | KDM4E (0.48) | KDM4EPKMSTSGPR119TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |