Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.53 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933718 | 0.92 | GPR119 (0.51) | GPR119BRD3KDM4EPKMTGFBR1 | |
| SCHEMBL30933748 | 0.91 | GPR119 (0.50) | GPR119BRD3KDM4EPKMTGFBR1 | |
| SCHEMBL30933724 | 0.89 | TGFBR1 (0.51) | GPR119KDM4EPKMTGFBR1HTR6 | |
| SCHEMBL30933838 | 0.88 | KDM4E (0.48) | GPR119KDM4EPKMTGFBR1HTR6 | |
| SCHEMBL30933815 | 0.87 | STS (0.52) | GPR119KDM4EPKMTGFBR1PDE4A | |
| SCHEMBL30933742 | 0.87 | KDM4E (0.46) | GPR119KDM4EPKMTGFBR1SCN9A | |
| SCHEMBL23686979 | 0.85 | GPR119 (0.55) | GPR119BRD3KDM4EPKMTGFBR1 | |
| SCHEMBL30933767 | 0.85 | GPR119 (0.49) | GPR119BRD3KDM4EPKMTGFBR1 | |
| SCHEMBL30933720 | 0.85 | DPP4 (0.47) | GPR119BRD3KDM4EPKMTGFBR1 | |
| SCHEMBL30933831 | 0.84 | GPR119 (0.49) | GPR119BRD3KDM4EPKMTGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |