SCHEMBL30933718

SCHEMBL30933718

CCCOc1ccc(F)cc1CNCC1CCN(C(=O)OC(C)(C)C)CC1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GPR119 Q8TDV5 5/20 0.51
HTR6 P50406 1/20 0.48
BRD3 Q15059 2/20 0.47
KDM4E B2RXH2 1/20 0.47
PKM P14618 1/20 0.47
SCN9A Q15858 1/20 0.47
TGFBR1 P36897 2/20 0.45
PDE4A P27815 2/20 0.44
PDE4B Q07343 2/20 0.44
PDE4C Q08493 2/20 0.44
PDE4D Q08499 2/20 0.44
DPP4 P27487 1/20 0.43
DNMT3A Q9Y6K1 1/20 0.42
RBP4 P02753 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30933767 0.93 GPR119 (0.49) GPR119HTR6BRD3KDM4EPKM
SCHEMBL30933731 0.92 GPR119 (0.53) GPR119HTR6BRD3KDM4EPKM
SCHEMBL30933748 0.90 GPR119 (0.50) GPR119HTR6BRD3KDM4EPKM
SCHEMBL30933771 0.89 PKM (0.47) GPR119HTR6KDM4EPKMSCN9A
SCHEMBL30933746 0.83 HTR6 (0.45) HTR6KDM4EPKM
SCHEMBL23686979 0.83 GPR119 (0.55) GPR119BRD3KDM4EPKMTGFBR1
SCHEMBL30933782 0.83 KDM4E (0.47) GPR119HTR6KDM4EPKMSCN9A
SCHEMBL30933831 0.83 GPR119 (0.49) GPR119HTR6BRD3KDM4EPKM
SCHEMBL30933770 0.81 KDM4E (0.47) GPR119HTR6KDM4EPKMSCN9A
SCHEMBL30933724 0.81 TGFBR1 (0.51) GPR119HTR6KDM4EPKMSCN9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024105007-A1 AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF Samsara Therapeutics Inc. (US) 2024-05-23 WO disclosed