Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 6/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933688 | 0.88 | POLB (0.50) | OPRL1BCHEACHEBACE1POLB | |
| SCHEMBL30933687 | 0.86 | MAPT (0.53) | OPRL1BCHEACHEBACE1POLB | |
| SCHEMBL30933655 | 0.85 | HTR2C (0.41) | OPRL1BCHEACHEBACE1POLB | |
| SCHEMBL29227125 | 0.81 | CCR5 (0.50) | PTGER1HTR2CHTR2BMEN1KMT2A | |
| SCHEMBL29227238 | 0.81 | CCR5 (0.60) | CCR5 | |
| SCHEMBL30873495 | 0.81 | CCR5 (0.60) | CCR5 | |
| SCHEMBL7666839 | 0.77 | CCR5 (0.51) | PTGER1HTR2CHTR2BMEN1KMT2A | |
| SCHEMBL30933787 | 0.77 | ALDH1A1 (0.48) | BCHEACHEBACE1POLBMEN1 | |
| SCHEMBL30933679 | 0.77 | NPBWR1 (0.47) | POLBHTR2CHTR2BMEN1KMT2A | |
| SCHEMBL22361728 | 0.77 | BCHE (0.66) | OPRL1BCHEACHEBACE1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |