Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.41 |
| ▸ | HTR2B | P41595 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30933889 | 0.82 | ANO1 (0.45) | CYP1A2CYP2D6POLBNPBWR1MCHR1 | |
| SCHEMBL30933775 | 0.81 | CYP1A2 (0.51) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| SCHEMBL30933688 | 0.80 | POLB (0.50) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| SCHEMBL30933796 | 0.80 | CYP1A2 (0.50) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| Hydrochloric Acid SCHEMBL30933747 | 0.80 | CYP1A2 (0.53) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| SCHEMBL30933787 | 0.79 | ALDH1A1 (0.48) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| SCHEMBL30933679 | 0.79 | NPBWR1 (0.47) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| SCHEMBL30933699 | 0.79 | NPBWR1 (0.49) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| Hydrochloric Acid SCHEMBL30933738 | 0.79 | CYP1A2 (0.52) | CYP1A2CYP2D6POLBATMNPBWR1 | |
| Hydrochloric Acid SCHEMBL30933669 | 0.78 | CYP1A2 (0.51) | CYP1A2CYP2D6POLBATMNPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |