Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 10/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 2/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822935 | 0.82 | ALDH1A1 (0.45) | HTR2AHTR2CHTR2BFFAR4KDM4E | |
| SCHEMBL27340554 | 0.81 | HPGD (0.40) | HTR2CHTR2B | |
| SCHEMBL24778694 | 0.78 | ALDH1A1 (0.38) | SCN9AKDM4EALDH1A1 | |
| SCHEMBL9110866 | 0.77 | HTR2A (0.39) | PARP15PARP10HTR2AHTR2CHTR2B | |
| SCHEMBL18783932 | 0.76 | MEN1 (0.49) | HTR2CHTR2BKDM4EALDH1A1 | |
| SCHEMBL4605658 | 0.76 | PDE4B (0.41) | PARP15PARP10HTR2AHTR2CHTR2B | |
| SCHEMBL17061451 | 0.76 | PTGDR2 (0.57) | ALDH1A1 | |
| SCHEMBL23040084 | 0.76 | PARP10 (0.55) | PARP15PARP10SCN9AFFAR4 | |
| SCHEMBL16150607 | 0.76 | HTR2C (0.46) | HTR2CHTR2BKDM4C | |
| SCHEMBL3642519 | 0.76 | ALDH1A1 (0.47) | PARP15PARP10HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105007-A1 | AUTOPHAGY INDUCING COMPOUNDS AND USES THEREOF | Samsara Therapeutics Inc. (US) | 2024-05-23 | — | — | WO | disclosed |