Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 1/20 | 0.55 |
| ▸ | F3 | P13726 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 3/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.47 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 3/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 3/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 3/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25253727 | 1.00 | F7 (0.55) | F7F3GABRA1GABRB2PRKAB2 | |
| SCHEMBL2056326 | 0.84 | GABRA1 (0.63) | F7F3GABRA1GABRB2GABRB1 | |
| SCHEMBL4232312 | 0.83 | KDM4E (0.57) | F7F3GABRA1GABRB2KDM4E | |
| SCHEMBL25025827 | 0.81 | GABRA1 (0.40) | F7F3GABRA1GABRB2LMNA | |
| SCHEMBL16431353 | 0.81 | F7 (0.51) | F7F3GABRA1GABRB2PRKAB2 | |
| SCHEMBL25253754 | 0.80 | STING1 (0.45) | GABRA1GABRB2KDM4EMEN1ALDH1A1 | |
| SCHEMBL23622949 | 0.79 | PRKAB2 (0.63) | F7F3GABRA1GABRB2PRKAB2 | |
| SCHEMBL6628762 | 0.79 | ALDH1A1 (0.51) | F7F3GABRA1GABRB2LMNA | |
| SCHEMBL17106890 | 0.79 | F7 (0.52) | F7F3GABRA1GABRB2PRKAB2 | |
| SCHEMBL396402 | 0.76 | GABRA1 (0.73) | GABRA1GABRB2KDM4EHTTGABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119595-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-05-31 | — | — | CN | disclosed |