Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.57 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 7/20 | 0.51 |
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.46 |
| ▸ | TDP2 | O95551 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HPD | P32754 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9024341 | 1.00 | PARP1 (0.57) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL30201259 | 0.91 | PARP1 (0.62) | PARP1PARP10MAOAMAOBPBRM1 | |
| SCHEMBL3680946 | 0.91 | PARP1 (0.62) | PARP1PARP10MAOAMAOBPBRM1 | |
| SCHEMBL18204573 | 0.86 | MAOA (0.46) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL9340005 | 0.86 | MAOA (0.46) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL5109850 | 0.86 | MAOB (0.62) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL7756401 | 0.82 | MAOA (0.48) | PARP1PARP10MAOAMAOBCYP2A6 | |
| SCHEMBL31026824 | 0.77 | PARP1 (0.47) | PARP1PARP10MAOAMAOBTDP2 | |
| SCHEMBL29235229 | 0.77 | PARP1 (0.47) | PARP1PARP10MAOAMAOBTDP2 | |
| SCHEMBL6247902 | 0.77 | TDP2 (0.55) | PARP1PARP10MAOAMAOBPBRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119595-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-05-31 | — | — | CN | disclosed |