Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.62 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.62 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.55 |
| ▸ | TDP2 | O95551 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 4/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR2B | P41595 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3680946 | 1.00 | PARP1 (0.62) | PARP1PARP10PBRM1TDP2ATM | |
| SCHEMBL30934632 | 0.91 | PARP1 (0.57) | PARP1PARP10PBRM1TDP2ATM | |
| SCHEMBL6247902 | 0.85 | TDP2 (0.55) | PARP1PARP10PBRM1TDP2MAOB | |
| SCHEMBL2388879 | 0.84 | CASP1 (0.55) | PARP1PARP10TDP2ATMNOTUM | |
| SCHEMBL31143658 | 0.80 | PBRM1 (0.55) | PARP1PARP10PBRM1ALDH1A1L3MBTL1 | |
| SCHEMBL6207175 | 0.80 | PBRM1 (0.55) | PARP1PARP10PBRM1ALDH1A1L3MBTL1 | |
| SCHEMBL1986133 | 0.78 | PARP1 (0.47) | PARP1PARP10PBRM1TDP2ATM | |
| SCHEMBL29235229 | 0.78 | PARP1 (0.47) | PARP1PARP10TDP2ATMNOTUM | |
| SCHEMBL31026824 | 0.78 | PARP1 (0.47) | PARP1PARP10TDP2ATMNOTUM | |
| SCHEMBL15467947 | 0.78 | PARP1 (0.51) | PARP1PARP10TDP2HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024223859-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2024-10-31 | — | — | WO | disclosed |
| WO-2024220917-A1 | PRMT5 INHIBITORS AND USES THEREOF | GILEAD SCIENCES, INC. (US) | 2024-10-24 | — | — | WO | disclosed |
| CN-111225875-B | Salt recovery solution and method of using salt recovery solution | 阿克福特斯技术有限公司 | 2023-04-11 | — | — | CN | disclosed |
| WO-2023028056-A1 | 3-AMINO PIPERIDYL SODIUM CHANNEL INHIBITORS | GENENTECH, INC. (US) | 2023-03-02 | — | — | WO | disclosed |