Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.43 |
| ▸ | RORC | P51449 | 3/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 3/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25026111 | 1.00 | NOTUM (0.43) | NOTUMRORCADRB1ADRB3PNMT | |
| SCHEMBL30233901 | 0.90 | AKR1C3 (0.40) | NOTUMRORCADRB1ADRB3HDAC8 | |
| SCHEMBL1016128 | 0.87 | PNMT (0.47) | NOTUMPNMTCNR2AADAT | |
| SCHEMBL14439414 | 0.85 | RORC (0.41) | RORC | |
| SCHEMBL30934719 | 0.83 | MAPT (0.41) | NOTUMHDAC8KMT2A | |
| SCHEMBL25026109 | 0.83 | MAPT (0.41) | NOTUMHDAC8KMT2A | |
| SCHEMBL11976231 | 0.82 | KIF11 (0.49) | NOTUM | |
| SCHEMBL24440190 | 0.80 | HDAC8 (0.42) | NOTUMHDAC8 | |
| SCHEMBL31262473 | 0.80 | HDAC8 (0.42) | NOTUMHDAC8 | |
| SCHEMBL31232515 | 0.79 | BRAF (0.45) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118119595-A | Compounds and compositions for the treatment of diseases associated with STING activity | 艾福姆德尤股份有限公司 | 2024-05-31 | — | — | CN | disclosed |