Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19384236 | 0.86 | KDM4E (0.38) | ALDH1A1FBP1EGFRHTR1ASLC6A4 | |
| SCHEMBL1346543 | 0.86 | SOD1 (0.39) | ALDH1A1FBP1EGFRHTR1ASLC6A4 | |
| SCHEMBL2276323 | 0.83 | ALDH1A1 (0.37) | ALDH1A1MAPTKDM4ETP53CYP3A4 | |
| SCHEMBL24701720 | 0.82 | NCF1 (0.44) | ALDH1A1MAPTTSHRTP53CYP3A4 | |
| SCHEMBL16386132 | 0.81 | TSHR (0.49) | MAPTTSHRKDM4EKCNH2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL27822532 | 0.81 | ALDH1A1 (0.36) | ALDH1A1MAPTTP53CYP3A4 | |
| SCHEMBL4364410 | 0.81 | KDM4E (0.41) | ALDH1A1MAPTFBP1HTR1ASLC6A4 | |
| SCHEMBL15071344 | 0.81 | KDM4E (0.41) | ALDH1A1MAPTTSHRKDM4E | |
| SCHEMBL19224011 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MAPTTSHRCYP3A4 | |
| SCHEMBL7627497 | 0.79 | MAPT (0.41) | ALDH1A1MAPTSLC6A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |