Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.33 |
| ▸ | BUB1 | O43683 | 2/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.31 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL867519 | 0.86 | GPR119 (0.44) | USP30GPR119UCHL1BACE1BACE2 | |
| SCHEMBL29911627 | 0.86 | GPR119 (0.44) | USP30GPR119UCHL1BACE1BACE2 | |
| SCHEMBL30697868 | 0.80 | ESR2 (0.37) | USP30GPR119UCHL1BACE1BACE2 | |
| SCHEMBL30697875 | 0.80 | ESR2 (0.37) | USP30GPR119UCHL1BACE1BACE2 | |
| SCHEMBL30935036 | 0.80 | GPR119 (0.33) | USP30GPR119PIM1PIM2BUB1 | |
| SCHEMBL30935347 | 0.78 | UCHL1 (0.42) | USP30GPR119PIM1PIM2BUB1 | |
| SCHEMBL29218282 | 0.77 | USP30 (0.42) | USP30GPR119PIM1PIM2BUB1 | |
| SCHEMBL30163103 | 0.77 | USP30 (0.42) | USP30GPR119PIM1PIM2BUB1 | |
| SCHEMBL28876530 | 0.77 | BUB1 (0.37) | USP30PIM1PIM2BUB1PRMT5 | |
| SCHEMBL24344110 | 0.77 | GPR119 (0.43) | USP30GPR119UCHL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |