Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL3 | P15374 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | WDR5 | P61964 | 4/20 | 0.40 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.39 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16099962 | 1.00 | UCHL3 (0.43) | UCHL3EGFRSMN1; SMN2MAPKAPK2GAA | |
| SCHEMBL16123380 | 0.81 | MAPKAPK2 (0.43) | UCHL3EGFRMAPKAPK2 | |
| SCHEMBL30934957 | 0.78 | JAK3 (0.41) | UCHL3EGFRCTSC | |
| SCHEMBL27361372 | 0.78 | UCHL3 (0.51) | UCHL3EGFRSMN1; SMN2MAPKAPK2GAA | |
| SCHEMBL16099915 | 0.78 | HIF1A (0.45) | EGFR | |
| SCHEMBL30380201 | 0.78 | HIF1A (0.45) | EGFR | |
| SCHEMBL16095969 | 0.77 | EGFR (0.58) | UCHL3EGFRSMN1; SMN2MAPKAPK2GAA | |
| SCHEMBL30226989 | 0.77 | CA1 (0.47) | EGFR | |
| SCHEMBL16095549 | 0.77 | HIF1A (0.42) | EGFR | |
| SCHEMBL16123326 | 0.77 | PDGFRB (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024125464-A1 | TETRAHYDROISOQUINOLIN-ONE DERIVATIVES, PREPARATION METHODS AND MEDICINAL USES THEREOF | JIANGSU HANSOH PHARMACEUTICAL GROUP CO., LTD. (CN) | 2024-06-20 | — | — | WO | disclosed |