Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25635684 | 0.84 | TBXAS1 (0.37) | KDM4EKMT2ATBXAS1ALDH1A1EGLN3 | |
| SCHEMBL13102475 | 0.79 | TBXAS1 (0.38) | KDM4EKMT2ATBXAS1ALDH1A1EGLN3 | |
| SCHEMBL25507659 | 0.79 | TBXAS1 (0.36) | KDM4EKMT2ATBXAS1ALDH1A1RAB9A | |
| SCHEMBL13102757 | 0.79 | TBXAS1 (0.48) | KDM4ETBXAS1ALDH1A1EGLN3FAAH | |
| SCHEMBL30935682 | 0.79 | FAAH (0.35) | KDM4EKMT2ATBXAS1ALDH1A1RAB9A | |
| SCHEMBL15730995 | 0.79 | TBXAS1 (0.35) | KDM4EKMT2ATBXAS1ALDH1A1EGLN3 | |
| SCHEMBL4211619 | 0.79 | TBXAS1 (0.35) | KDM4EKMT2ATBXAS1ALDH1A1EGLN3 | |
| SCHEMBL4211623 | 0.79 | TBXAS1 (0.35) | KDM4EKMT2ATBXAS1ALDH1A1EGLN3 | |
| SCHEMBL13518237 | 0.77 | ADRB2 (0.32) | KDM4ETBXAS1EGLN3 | |
| SCHEMBL22047552 | 0.77 | TBXAS1 (0.46) | TBXAS1ALDH1A1EGLN3FAAHMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4630424-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | Third Harmonic Bio, Inc. (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024124002-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | THIRD HARMONIC BIO, INC. (US) | 2024-06-13 | — | — | WO | disclosed |