Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 5/20 | 0.69 |
| ▸ | CNR2 | P34972 | 2/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.46 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2919759 | 0.89 | CNR1 (0.58) | CNR1CNR2ALDH1A1TSHRPOLB | |
| SCHEMBL2915869 | 0.81 | CYP2C9 (0.63) | CNR1CNR2ALDH1A1SMN1; SMN2NPSR1 | |
| SCHEMBL2918283 | 0.79 | ALDH1A1 (0.55) | CNR1CNR2ALDH1A1POLBUSP2 | |
| SCHEMBL30936703 | 0.78 | CNR1 (0.60) | CNR1CNR2ALDH1A1LMNAHPGD | |
| SCHEMBL30936648 | 0.76 | CNR1 (0.67) | CNR1CNR2ALDH1A1TSHRLMNA | |
| SCHEMBL2913926 | 0.75 | MGLL (0.50) | CNR1CNR2ALDH1A1TSHRPOLB | |
| SCHEMBL16197600 | 0.75 | CNR1 (0.90) | CNR1CNR2LMNANPSR1CYP2C9 | |
| SCHEMBL2919412 | 0.74 | ALDH1A1 (0.73) | CNR1CNR2ALDH1A1HPGDNPSR1 | |
| SCHEMBL4781711 | 0.73 | CNR1 (0.73) | CNR1CNR2LMNANPSR1CYP2C9 | |
| SCHEMBL18353073 | 0.73 | CNR1 (0.54) | CNR1CNR2ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092205-A1 | INHIBITION OF SHIP1 AS A THERAPEUTIC STRATEGY FOR THE TREATMENT OF ALZHEIMER'S DISEASE | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-05-02 | — | — | WO | disclosed |