Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 19/20 | 0.65 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.55 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936898 | 0.88 | EGFR (0.67) | EGFR | |
| SCHEMBL27076040 | 0.88 | EGFR (0.58) | EGFRZAP70LRRK2 | |
| SCHEMBL30936793 | 0.88 | EGFR (0.60) | EGFRZAP70 | |
| SCHEMBL30936957 | 0.87 | EGFR (0.67) | EGFRZAP70LRRK2 | |
| SCHEMBL27076010 | 0.86 | EGFR (0.63) | EGFRZAP70 | |
| SCHEMBL30937137 | 0.85 | EGFR (0.63) | EGFR | |
| SCHEMBL30936888 | 0.85 | EGFR (0.65) | EGFR | |
| SCHEMBL27076035 | 0.84 | EGFR (0.56) | EGFRZAP70LRRK2 | |
| SCHEMBL24817685 | 0.83 | ALK (0.66) | EGFR | |
| SCHEMBL30936997 | 0.83 | EGFR (0.51) | EGFRZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |