Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 18/20 | 0.51 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.45 |
| ▸ | INSR | P06213 | 1/20 | 0.45 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30936873 | 0.91 | EGFR (0.50) | EGFRALKINSRZAP70 | |
| SCHEMBL27076010 | 0.83 | EGFR (0.63) | EGFRALKINSRZAP70 | |
| SCHEMBL30936862 | 0.83 | EGFR (0.65) | EGFRZAP70 | |
| SCHEMBL30936779 | 0.83 | EGFR (0.56) | EGFR | |
| SCHEMBL30936863 | 0.82 | EGFR (0.59) | EGFRZAP70 | |
| SCHEMBL30936802 | 0.81 | EGFR (0.59) | EGFR | |
| SCHEMBL27076040 | 0.80 | EGFR (0.58) | EGFRALKINSRZAP70 | |
| SCHEMBL30936898 | 0.80 | EGFR (0.67) | EGFRALKINSR | |
| SCHEMBL24817687 | 0.78 | ALK (0.63) | EGFRALKINSR | |
| SCHEMBL30936272 | 0.78 | PTK2 (0.47) | EGFRALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024072178-A1 | COMPOUND FOR TARGETED PROTEIN DEGRADATION, AND USE THEREOF | (주)사이러스테라퓨틱스 | 2024-04-04 | — | — | WO | disclosed |