Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 8/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.35 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | MMP13 | P45452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937643 | 0.85 | MMP13 (0.41) | ALDH1A1KDM4EKMT2APLA2G10PLA2G5 | |
| SCHEMBL30937590 | 0.84 | SCN9A (0.38) | ALDH1A1KDM4EGPR119RIPK1PLA2G10 | |
| SCHEMBL30937550 | 0.83 | ACE (0.45) | ALDH1A1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL30937570 | 0.82 | ACE (0.36) | RIPK1ACEMMP13 | |
| SCHEMBL30937741 | 0.79 | ACE (0.36) | ALDH1A1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL30937599 | 0.73 | DRD2 (0.39) | ALDH1A1KDM4EMEN1MAPTRAB9A | |
| SCHEMBL30937608 | 0.72 | ACE (0.42) | ALDH1A1KDM4EPLA2G10PLA2G5MAPK1 | |
| SCHEMBL30937730 | 0.71 | ACE (0.49) | ALDH1A1KDM4EMEN1RAB9AKMT2A | |
| SCHEMBL30937656 | 0.71 | ACE (0.37) | ALDH1A1KDM4EPLA2G10PLA2G5MAPK1 | |
| SCHEMBL30937552 | 0.68 | PLA2G10 (0.38) | PLA2G10PLA2G5MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594307-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073426-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |