Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 11/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937665 | 0.82 | ACE (0.47) | ACEMMP13ITGB3ITGA2B | |
| SCHEMBL30937659 | 0.82 | ALDH1A1 (0.36) | ACEMMP13RIPK1 | |
| SCHEMBL30937672 | 0.75 | ACE (0.41) | ACEMMP13STAT3 | |
| SCHEMBL30937588 | 0.67 | ACE (0.48) | ACEMMP13ITGB3ITGA2B | |
| SCHEMBL30937524 | 0.66 | ACE (0.44) | ACEMMP13 | |
| SCHEMBL30937732 | 0.66 | ACE (0.44) | ACEMMP13 | |
| SCHEMBL30937651 | 0.66 | ACE (0.53) | ACEMMP13 | |
| SCHEMBL8345781 | 0.64 | TSHR (0.39) | ACEMMP13 | |
| SCHEMBL30937679 | 0.64 | BRD4 (0.51) | ACEMMP13 | |
| SCHEMBL30937681 | 0.64 | ACE (0.42) | ACEMMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594307-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073426-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |