Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622777 | 0.82 | TAAR1 (0.37) | LOXL2TAAR1 | |
| SCHEMBL16613034 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL6652156 | 0.79 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL16812300 | 0.74 | TAAR1 (0.45) | DPP4TAAR1 | |
| SCHEMBL30818217 | 0.74 | TAAR1 (0.45) | DPP4TAAR1 | |
| SCHEMBL6673395 | 0.74 | IMPDH2 (0.44) | ALDH1A1 | |
| SCHEMBL29950776 | 0.74 | CTSL (0.33) | ALDH1A1 | |
| SCHEMBL111658 | 0.71 | TAAR1 (0.47) | ALDH1A1LOXL2DPP4TAAR1 | |
| SCHEMBL9032040 | 0.71 | F2RL1 (0.33) | — | |
| SCHEMBL112835 | 0.71 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4594307-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2025-08-06 | — | — | EP | disclosed |
| WO-2024073426-A1 | 1,4-DIHYDROQUINAZOLINONE COMPOUNDS AND USES THEREOF | EDGEWISE THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |