Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 4/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24840121 | 0.90 | P2RX7 (0.37) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL30414499 | 0.76 | MAPK1 (0.34) | P2RX7MAPK1 | |
| SCHEMBL25419802 | 0.76 | MAPK1 (0.34) | P2RX7MAPK1 | |
| SCHEMBL30768992 | 0.76 | LPL (0.37) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL24374129 | 0.74 | P2RX7 (0.34) | P2RX7 | |
| SCHEMBL18328347 | 0.72 | LPL (0.38) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL30973518 | 0.72 | — | — | |
| SCHEMBL21732624 | 0.71 | P2RX7 (0.37) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL10158544 | 0.71 | P2RX7 (0.37) | P2RX7MAPK1LPLLIPG | |
| SCHEMBL30042926 | 0.71 | P2RX7 (0.37) | P2RX7MAPK1LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4615841-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-09-17 | — | — | EP | disclosed |
| WO-2025045961-A1 | INHIBITORS OF THE NLRP3 INFLAMMASOME | F. HOFFMANN-LA ROCHE AG (CH) | 2025-03-06 | — | — | WO | disclosed |
| WO-2024099992-A1 | TRIAZINONE DERIVATIVES AS NLRP3 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2024-05-16 | — | — | WO | disclosed |