Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | ACE | P12821 | 1/20 | 0.48 |
| ▸ | CPA1 | P15085 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 9/20 | 0.48 |
| ▸ | NPY1R | P25929 | 7/20 | 0.48 |
| ▸ | NPY2R | P49146 | 5/20 | 0.48 |
| ▸ | NPY5R | Q15761 | 5/20 | 0.48 |
| ▸ | CDK4 | P11802 | 1/20 | 0.47 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.47 |
| ▸ | CCND1 | P24385 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30810237 | 0.93 | F2 (0.52) | F2MMEACECPA1ACE2 | |
| SCHEMBL30541920 | 0.92 | GNPAT (0.52) | MMEACECPA1ACE2NPY4R | |
| SCHEMBL29608079 | 0.91 | KISS1R (0.57) | NPY4RNPY1RNPY2RNPY5RCDK4 | |
| SCHEMBL30572369 | 0.89 | NPY4R (0.52) | F2NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL31277463 | 0.89 | ENPEP (0.46) | — | |
| SCHEMBL30303032 | 0.89 | ENPEP (0.46) | — | |
| SCHEMBL31206418 | 0.88 | GRB2 (0.51) | F2MMEACECPA1ACE2 | |
| SCHEMBL31657686 | 0.87 | F2 (0.48) | F2KISS1R | |
| SCHEMBL31318675 | 0.87 | ENPEP (0.47) | — | |
| SCHEMBL7414767 | 0.86 | F2 (0.49) | F2NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4389893-A1 | HUMAN TRANSFERRIN RECEPTOR BINDING PEPTIDE-DRUG CONJUGATE | Takeda Pharmaceutical Company Limited (JP) | 2024-06-26 | — | — | EP | disclosed |